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5-MTHF + B12

Fixes a shortfall. Little proof beyond that.

B

Grade B: Some human proof

Small, early or mixed results in people.

The grade is for the use people talk about, not for every use. Filed under: Health and wellness, over the counter.

How it works

The active forms of folate and vitamin B12, used to make DNA and red blood cells.

How it was given in studies

By mouth. In the trials people swallowed it as a capsule, tablet, powder or drink.

This is what the studies did. It is not a how-to.

What studies saw

Reliably corrects low folate or B12. Little proof of benefit when levels are already normal.

The trade-off

High folate can fix the anemia of a B12 shortfall while nerve damage continues. That is one reason the two are paired.

When it showed up, in studies

1 to 3 months

Low folate or B12 corrects over weeks to months.

Sources

  1. NIH folate fact sheet
  2. Review of 15 trials
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5-MTHF + B12: grade B, some human proof. Worked in Rats

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Keep going

We show what studies found. We never tell you what to take. Doses vary by study. Check the sources and talk to a doctor.