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Alpha-GPC

Small trials. One large study raised a stroke question.

B

Grade B: Some human proof

Small, early or mixed results in people.

The grade is for the use people talk about, not for every use. Filed under: Brain support, over the counter.

How it works

Delivers choline to the brain to make acetylcholine, a memory signal.

How it was given in studies

By mouth. In the trials people swallowed it as a capsule, tablet, powder or drink.

This is what the studies did. It is not a how-to.

What studies saw

Small trials in young men: a better score on one attention test an hour after a dose, and more jump power or leg strength after about a week. Other measures did not move. In South Korea it is a prescription drug widely used for dementia symptoms.

The trade-off

A Korean records study of about 12 million people linked use to a higher 10-year stroke risk. That kind of study cannot prove cause.

When it showed up, in studies

Same day

One small trial: a better score on one attention test an hour after a dose.

First few weeks

More jump power or leg strength after about a week, in small trials.

Sources

  1. Korean stroke records study
  2. Single-dose trial, 20 men
  3. One-week trial, 48 men
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Alpha-GPC: grade B, some human proof. Worked in Rats

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Keep going

We show what studies found. We never tell you what to take. Doses vary by study. Check the sources and talk to a doctor.