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CoQ10

Best result is in heart failure.

B

Grade B: Some human proof

Small, early or mixed results in people.

The grade is for the use people talk about, not for every use. Filed under: Health and wellness, over the counter.

How it works

Helps cells make energy. Statin drugs lower the body's own supply.

How it was given in studies

By mouth. In the trials people swallowed it as a capsule, tablet, powder or drink.

This is what the studies did. It is not a how-to.

What studies saw

In a two-year trial of 420 heart failure patients, major heart events hit 15% on CoQ10, against 26% on placebo. A review of 12 small trials found it eased statin muscle aches.

The trade-off

Absorbs poorly. It may weaken the blood thinner warfarin, but the proof is thin.

When it showed up, in studies

First few weeks

Blood levels build over a few weeks.

3 months or more

The main heart failure trial ran two years.

Sources

  1. Trial in 420 patients
  2. Review of 12 trials
  3. Review of seven trials
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Keep going

See how CoQ10 mixes with others in the stack builder → Over-the-counter supplements: the claims, checked →

We show what studies found. We never tell you what to take. Doses vary by study. Check the sources and talk to a doctor.