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Glutamine

One striking IBS trial. Pooled data show no clear change.

B

Grade B: Some human proof

Small, early or mixed results in people.

The grade is for the use people talk about, not for every use. Filed under: Gut health.

How it works

An amino acid that the cells lining the gut use as fuel.

How it was given in studies

By mouth. In the trials people swallowed it as a capsule, tablet, powder or drink.

This is what the studies did. It is not a how-to.

What studies saw

In an 8-week trial of 106 people with diarrhea-type IBS after a gut infection, about 80% improved, against 6% on placebo. Ten smaller trials in other illnesses, pooled, showed no clear change in gut leakiness.

The trade-off

The big result comes from one trial in one kind of IBS. Its authors called for larger ones.

When it showed up, in studies

1 to 3 months

8 weeks in the one positive trial.

Sources

  1. IBS trial
  2. Review of 10 trials
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Keep going

We show what studies found. We never tell you what to take. Doses vary by study. Check the sources and talk to a doctor.