Kisspeptin
Switches on sex hormones within minutes. Single-session studies only.
Grade B: Some human proof
Small, early or mixed results in people.
The grade is for the use people talk about, not for every use. Filed under: Libido and sex hormones.
How it works
A natural brain peptide that tells the body to release LH, the hormone that drives testosterone and ovulation.
How it was given in studies
Into a vein, as an injection or a drip, during single lab sessions.
This is what the studies did. It is not a how-to. Source: Kisspeptin-10 in healthy men. JCEM, 2011; Trial in men with low desire. JAMA Network Open, 2023.
What studies saw
In 6 healthy men, one dose of kisspeptin-10 roughly tripled LH within 30 minutes, and a day-long drip raised testosterone. In 32 men with low desire, one drip of kisspeptin-54 changed brain responses to sexual images and raised arousal more than placebo.
The trade-off
Each study was a single session in a research clinic. We found no study of repeat use. FDA says it has little or no safety information on kisspeptin-10.
When it showed up, in studies
LH rises within 30 minutes.
No study of repeat use.
Sources
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Keep going
We show what studies found. We never tell you what to take. Doses vary by study. Check the sources and talk to a doctor.