KPV
Calmed gut inflammation in mice. No human study.
Grade C: Animals and lab only
Looks good in rats or in a dish. Not proven in people.
The grade is for the use people talk about, not for every use. Filed under: Gut health.
How it works
The last three amino acids of the body's pigment hormone, alpha-MSH. In lab work it turns down inflammation signals.
How it was given in studies
No published human study, so no route has been tested in people.
This is what the studies did. It is not a how-to.
What studies saw
Given by mouth, it eased colitis in mice, in studies from two teams. We found no human study, published or registered.
The trade-off
FDA says it found no human exposure data at all, so nobody knows if it is safe in people.
When it showed up, in studies
No human studies.
Sources
Put this grade on your site
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Keep going
We show what studies found. We never tell you what to take. Doses vary by study. Check the sources and talk to a doctor.