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Metformin

A diabetes drug. No finished aging trial.

B

Grade B: Some human proof

Small, early or mixed results in people.

The grade is for the use people talk about, not for every use. Filed under: Longevity.

How it works

A prescription diabetes drug that lowers blood sugar.

How it was given in studies

By mouth. It is a tablet.

This is what the studies did. It is not a how-to. Source: FDA label on DailyMed.

What studies saw

We found no finished trial that tested it against aging in people.

The trade-off

In a 14-week trial of 94 older adults doing strength training, the placebo group gained more muscle.

When it showed up, in studies

1 to 3 months

Less muscle gain than placebo over 14 weeks of lifting, in older adults.

Sources

  1. Trial in 94 older adults
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Metformin: grade B, some human proof. Worked in Rats

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Keep going

We show what studies found. We never tell you what to take. Doses vary by study. Check the sources and talk to a doctor.