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NAC

An approved hospital drug. Mixed results as a supplement.

B

Grade B: Some human proof

Small, early or mixed results in people.

The grade is for the use people talk about, not for every use. Filed under: Health and wellness, over the counter.

How it works

Gives the body a building block for glutathione, an antioxidant inside cells.

How it was given in studies

By mouth. In the trials people swallowed it as a capsule, tablet, powder or drink.

This is what the studies did. It is not a how-to.

What studies saw

An FDA-approved hospital antidote for acetaminophen overdose. In chronic bronchitis trials it cut flare-ups. A review of seven studies found no real gain in exercise performance.

The trade-off

The drug label lists nausea and vomiting. In the bronchitis trials, stomach complaints were about as common on placebo. The FDA says it does not count as a supplement, but allows it to be sold as one for now.

When it showed up, in studies

3 months or more

Fewer bronchitis flare-ups in trials that ran 12 to 24 weeks.

No timeline in people yet

No timeline as a daily supplement for healthy people.

Sources

  1. Review of 11 bronchitis trials
  2. Review of exercise studies
  3. FDA statement on NAC
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Keep going

We show what studies found. We never tell you what to take. Doses vary by study. Check the sources and talk to a doctor.