Rapamycin
Longer-lived mice. A one-year human trial missed its main goal.
Grade B: Some human proof
Small, early or mixed results in people.
The grade is for the use people talk about, not for every use. Filed under: Longevity.
How it works
A prescription drug that blocks mTOR, a growth switch inside cells.
How it was given in studies
By mouth. The approved drug is a tablet, and the aging trial used capsules.
This is what the studies did. It is not a how-to. Source: FDA label on DailyMed; Aging trial record on ClinicalTrials.gov.
What studies saw
Mice lived longer. In a 48-week trial in healthy adults, belly fat did not change. Lean mass and pain improved only in women in one group.
The trade-off
No study shows people live longer. Every author of the human trial worked for the company that ran it.
When it showed up, in studies
A 48-week trial in healthy adults missed its main goal.
Sources
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Keep going
We show what studies found. We never tell you what to take. Doses vary by study. Check the sources and talk to a doctor.