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Sermorelin

A former prescription drug for children. The adult evidence is tiny.

B

Grade B: Some human proof

Small, early or mixed results in people.

The grade is for the use people talk about, not for every use. Filed under: Growth hormone boosters.

How it works

A copy of the working end of the body's own growth-hormone-releasing hormone. It tells the pituitary to release growth hormone.

How it was given in studies

Injection under the skin. The adults in the study injected themselves.

This is what the studies did. It is not a how-to. Source: Trial in 19 older adults. JCEM, 1997.

What studies saw

FDA approved it in 1997 for children who were not growing because of low growth hormone. In 19 adults aged 55 to 71 given a close copy for 16 weeks, growth hormone rose, skin got thicker, and lean mass rose in men only.

The trade-off

The maker stopped selling it in 2008. FDA found that was not over safety or effectiveness. The adult trial was small and single-blind, and blood fats rose for a while.

When it showed up, in studies

Same day

A growth hormone pulse within minutes.

3 months or more

Lean mass rose in men over 16 weeks, in one small trial.

Sources

  1. Trial in 19 older adults
  2. FDA notice on Geref
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Sermorelin: grade B, some human proof. Worked in Rats

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We show what studies found. We never tell you what to take. Doses vary by study. Check the sources and talk to a doctor.