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Thymosin alpha-1

A hepatitis drug abroad. Not approved in the US.

B

Grade B: Some human proof

Small, early or mixed results in people.

The grade is for the use people talk about, not for every use. Filed under: Longevity.

How it works

A lab-made copy of a peptide from the thymus, a gland that helps train immune cells.

How it was given in studies

Injection under the skin, in a sepsis trial of 1,106 adults.

This is what the studies did. It is not a how-to. Source: Sepsis trial. BMJ, 2025.

What studies saw

Used in other countries mainly for hepatitis B and C. In 1,106 adults with sepsis, deaths were about the same as placebo.

The trade-off

No trial has tested whether it helps healthy people. The FDA says there is too little safety information on compounded versions.

When it showed up, in studies

No timeline in people yet

No timeline in healthy people.

Sources

  1. Trial in 1,106 adults
  2. 2009 review
  3. FDA safety risk list
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Thymosin alpha-1: grade B, some human proof. Worked in Rats

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Keep going

We show what studies found. We never tell you what to take. Doses vary by study. Check the sources and talk to a doctor.