Tirzepatide
FDA-approved. Prescription only.
Grade A: Strong human proof
Big trials in people, and it worked.
The grade is for the use people talk about, not for every use. Filed under: Fat loss (GLP-1 family).
How it works
Copies two gut hormones, GLP-1 and GIP.
How it was given in studies
Injection under the skin, in the trials and on the FDA label.
This is what the studies did. It is not a how-to. Source: Stopping trial. JAMA, 2024; FDA label on DailyMed.
What studies saw
About 21% of body weight lost at the top dose over 72 weeks, against 3% on placebo.
The trade-off
Same stomach side effects as the rest of the family. Weight tends to come back after stopping.
When it showed up, in studies
Appetite drops in the first weeks.
About 21% of body weight at the top dose over 72 weeks.
Sources
Put this grade on your site
Copy the line below. The badge links back to this page, so readers can check the sources. It grades the compound in studies. It does not rate any product or seller.
<a href="https://www.workedinrats.com/compounds/tirzepatide"><img src="https://www.workedinrats.com/badge/tirzepatide.svg" alt="Tirzepatide: grade A, strong human proof. Worked in Rats" width="300" height="72"></a>
Keep going
We show what studies found. We never tell you what to take. Doses vary by study. Check the sources and talk to a doctor.